FNBP4

Across TCGA pan-cancer cohorts, FNBP4 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of FNBP4’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where FNBP4 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types FNBP4 is over-expressed in tumor, although a few such as KICH and BRCA show the opposite, repressed pattern.

COAD, KIRC, and LIHC are the cancer types where FNBP4 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FNBP4 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Male	II,III,IV	+0.864	<.001	10	view →
KIRC	Female	All	+0.520	<.001	9	view →
LIHC	Female	II,III,IV	+1.170	<.001	8	view →
HNSC	All	All	+0.395	.003	6	view →
CHOL	All	All	+2.016	<.001	5	view →
KICH	Female	All	−1.006	<.001	5	view →
STAD	All	II,III,IV	+0.709	.007	4	view →
KIRP	All	IV	+0.860	.030	2	view →
READ	All	All	+0.796	.003	2	view →
ESCA	Female	All	+0.493	.007	2	view →
BRCA	Female	All	−0.186	.039	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

FNBP4–COAD

Open the COAD breakdown →