FMR1-IT1

Across TCGA patient cohorts, FMR1-IT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,165 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible FMR1-IT1-associated GO terms across cancer lineages are Regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, Regulation of chromatin organization, and Regulation of telomere maintenance via telomere lengthening. Each is linked with FMR1-IT1 in more than 32 cancer types. Because this analysis shows association rather than direction, both FMR1-IT1-to-partner and partner-to-FMR1-IT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay grouped by FMR1-IT1-low versus FMR1-IT1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FMR1-IT1→partner) and Y-score (partner→FMR1-IT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay →	+0.067	+0.510	<.001	<.001	3	33
DLBC	Regulation of chromatin organization →	+0.088	+1.302	.001	<.001	3	33
DLBC	Regulation of telomere maintenance via telomere lengthening →	+0.074	+1.154	<.001	<.001	3	33
DLBC	Protein localization to microtubule organizing center →	+0.075	+1.072	<.001	<.001	3	33
UCS	Regulation of nucleotide-excision repair →	+0.068	+0.786	<.001	<.001	3	33
ESCA	Positive regulation of chromosome organization →	+0.067	+0.928	<.001	<.001	3	33

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,165 associations by consensus.

Regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay by FMR1-IT1 expression — STAD

Explore this box plot interactively →