FMO5

Across TCGA cell cohorts, FMO5 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FMO5-associated genes across cancer lineages are LILRA1, GAGE12H, and CCR8. Each is linked with FMO5 in more than 1 cancer types. Because this analysis shows association rather than direction, both FMO5-to-partner and partner-to-FMO5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LILRA1 grouped by FMO5-low versus FMO5-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FMO5→partner) and Y-score (partner→FMO5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	LILRA1 →	+0.006	+4.906	<.001	.006	3	1
OESOPHAGUS	GAGE12H →	+0.053	+4.906	<.001	.006	3	1
SOFT_TISSUE	CCR8 →	+0.022	+5.369	<.001	.004	3	1
SOFT_TISSUE	FAM205C →	+0.063	+4.930	<.001	.008	3	1
URINARY_TRACT	CCDC178 →	+0.040	+5.087	<.001	.004	3	1
LARGE_INTESTINE	TKTL2 →	+0.054	+4.187	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

LILRA1 by FMO5 expression — OESOPHAGUS

Explore this box plot interactively →