FMC1-LUC7L2

Across TCGA patient cohorts, FMC1-LUC7L2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,950 significant associations in total. LGG shows the largest number of these associations.

The most reproducible FMC1-LUC7L2-associated GO terms across cancer lineages are Negative regulation of telomere capping, Regulation of autophagosome assembly, and Telomere capping. Each is linked with FMC1-LUC7L2 in more than 20 cancer types. Because this analysis shows association rather than direction, both FMC1-LUC7L2-to-partner and partner-to-FMC1-LUC7L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of telomere capping grouped by FMC1-LUC7L2-low versus FMC1-LUC7L2-high in TGCT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FMC1-LUC7L2→partner) and Y-score (partner→FMC1-LUC7L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
TGCT	Negative regulation of telomere capping →	+0.051	+0.097	<.001	<.001	3	21
THYM	Regulation of autophagosome assembly →	+0.033	+0.065	<.001	<.001	3	18
THYM	Telomere capping →	+0.036	+0.080	<.001	<.001	3	18
TGCT	Negative regulation of telomere maintenance via telomere lengthening →	+0.037	+0.080	<.001	<.001	3	18
THYM	Ribosome-associated ubiquitin-dependent protein catabolic process →	+0.055	+0.062	<.001	<.001	3	18
THYM	Protein localization to phagophore assembly site →	+0.043	+0.065	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,950 associations by consensus.

Negative regulation of telomere capping by FMC1-LUC7L2 expression — TGCT

Explore this box plot interactively →