FMC1-LUC7L2

Across TCGA pan-cancer cohorts, FMC1-LUC7L2 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated FMC1-LUC7L2 data layer compared with 1 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher FMC1-LUC7L2 RNA is associated with better overall survival. In most high-consensus cancer types, elevated FMC1-LUC7L2 expression acts as an unfavorable survival marker, although some lineages such as HNSC and KIRC show a favorable association.

HNSC, SKCM, and ESCA are the cancer types where FMC1-LUC7L2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	III,IV	0.429	0.187	<.001	148	view →
SKCM	OS	Quartile	All	0.162	0.490	<.001	51	view →
ESCA	OS	Quartile	IV	0.127	0.601	.017	30	view →
KIRC	DFS	Quartile	All	0.717	0.554	.006	26	view →
COAD	DFS	Quartile	II,III,IV	0.623	0.792	.005	22	view →
BLCA	DFS	Quartile	II,III,IV	0.533	0.661	.019	18	view →
READ	DFS	Quartile	III,IV	0.217	0.787	.001	12	view →
LUAD	DFS	Quartile	All	0.535	0.323	.013	9	view →
THCA	OS	Median	III,IV	0.963	0.761	.003	8	view →
DLBC	DFS	Tertile	II,III,IV	0.537	1.000	.020	8	view →
PCPG	DFS	Median	All	0.868	0.964	.007	7	view →
THYM	OS	Median	II,III,IV	1.000	0.706	.015	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

FMC1-LUC7L2–HNSC (OS)

Open the HNSC breakdown →