Across TCGA pan-cancer cohorts, FMC1-LUC7L2 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of FMC1-LUC7L2’s most consistent transcriptional readouts.
The strongest signal is observed in stomach adenocarcinoma (STAD), where FMC1-LUC7L2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types FMC1-LUC7L2 is over-expressed in tumor.
STAD are the cancer types where FMC1-LUC7L2 tumor–normal differential expression is most reproducible.