FMC1-LUC7L2

Across TCGA cell cohorts, FMC1-LUC7L2 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FMC1-LUC7L2-associated genes across cancer lineages are SCGB1C1, FCN2, and MMP26. Each is linked with FMC1-LUC7L2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FMC1-LUC7L2-to-partner and partner-to-FMC1-LUC7L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SCGB1C1 grouped by FMC1-LUC7L2-low versus FMC1-LUC7L2-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FMC1-LUC7L2→partner) and Y-score (partner→FMC1-LUC7L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	SCGB1C1 →	+0.242	+4.981	<.001	.008	3	1
LARGE_INTESTINE	FCN2 →	+0.033	+4.415	<.001	<.001	3	1
LARGE_INTESTINE	MMP26 →	+0.039	+3.632	<.001	.003	3	1
LARGE_INTESTINE	ANO5 →	+0.704	+3.453	<.001	.009	3	1
LARGE_INTESTINE	FAM205A →	+0.019	+3.766	.001	.004	3	1
LARGE_INTESTINE	OR5V1 →	+0.006	+4.022	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

SCGB1C1 by FMC1-LUC7L2 expression — CNS

Explore this box plot interactively →