FLYWCH2

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FLYWCH2 mutation is significantly associated with the total protein of many other genes, with 1 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FLYWCH2-associated genes across cancer lineages are Ku80. Each is linked with FLYWCH2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FLYWCH2-to-partner and partner-to-FLYWCH2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ku80 grouped by FLYWCH2-low versus FLYWCH2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FLYWCH2→partner) and Y-score (partner→FLYWCH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECKu80 →+0.385+2.820.007.03611
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

Ku80 by FLYWCH2 expression — UCEC

Box plot of Ku80 in FLYWCH2-low vs FLYWCH2-high samples in UCEC.

Explore this box plot interactively →

Exploration