FKBP6

Across TCGA cell cohorts, FKBP6 RNA expression is significantly associated with the go_rna of many other GO terms, with 877 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible FKBP6-associated GO terms across cancer lineages are Purine nucleoside triphosphate biosynthetic process, Purine ribonucleoside triphosphate biosynthetic process, and Nuclear-transcribed mRNA catabolic process. Each is linked with FKBP6 in more than 4 cancer types. Because this analysis shows association rather than direction, both FKBP6-to-partner and partner-to-FKBP6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Purine nucleoside triphosphate biosynthetic process grouped by FKBP6-low versus FKBP6-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FKBP6→partner) and Y-score (partner→FKBP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Purine nucleoside triphosphate biosynthetic process →	+0.084	+0.092	<.001	.003	3	4
LUNG_NSCLC_LUSC	Purine ribonucleoside triphosphate biosynthetic process →	+0.084	+0.092	<.001	.003	3	4
LUNG_NSCLC_LUSC	Nuclear-transcribed mRNA catabolic process →	+0.051	+0.093	.002	.005	3	4
LARGE_INTESTINE	Transferrin transport →	+0.075	+0.026	.002	.007	3	4
LUNG_SCLC	Regulation of lymphotoxin A production →	-0.633	-0.193	.009	.007	3	4
LUNG_SCLC	Positive regulation of lymphotoxin A production →	-0.633	-0.193	.009	.007	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 877 associations by consensus.

Purine nucleoside triphosphate biosynthetic process by FKBP6 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →