FKBP6

Across TCGA pan-cancer cohorts, FKBP6 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of FKBP6’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where FKBP6 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types FKBP6 is over-expressed in tumor, although a few such as BRCA show the opposite, repressed pattern.

KIRP, CHOL, and LIHC are the cancer types where FKBP6 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FKBP6 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	All	All	+0.069	<.001	6	view →
CHOL	All	All	+0.093	.003	2	view →
LIHC	All	All	+0.048	.028	2	view →
BRCA	All	III,IV	−0.026	.012	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

FKBP6–KIRP

Open the KIRP breakdown →