FKBP6

Across TCGA pan-cancer cohorts, FKBP6 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated FKBP6 data layer compared with 7 for mutation status and 1 for mass-spec protein.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher FKBP6 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated FKBP6 expression acts as an unfavorable survival marker, although some lineages such as LUAD and BRCA show a favorable association.

KIRC, THCA, and MESO are the cancer types where FKBP6 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Quartile	All	0.547	0.728	.001	33	view →
THCA	DFS	Median	All	0.847	0.958	.008	29	view →
MESO	DFS	Tertile	III,IV	0.260	0.487	.009	21	view →
LUAD	DFS	Quartile	All	0.864	0.655	.001	21	view →
UVM	DFS	Median	III,IV	0.209	0.885	.001	20	view →
ACC	DFS	Tertile	All	0.315	0.745	.029	17	view →
STAD	OS	Quartile	II,III,IV	0.559	0.820	.015	14	view →
BRCA	OS	Quartile	III,IV	0.761	0.460	.020	11	view →
UCS	OS	Quartile	II,III,IV	0.753	0.323	.024	10	view →
KICH	OS	Quartile	All	1.000	0.520	.031	8	view →
KIRP	DFS	Quartile	All	0.941	0.655	.044	8	view →
CESC	DFS	Tertile	All	0.626	0.445	.010	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

FKBP6–KIRC (OS)

Open the KIRC breakdown →