FKBP6

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, FKBP6 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible FKBP6-associated genes across cancer lineages are SULT6B1 and OR5M3. Each is linked with FKBP6 in more than 1 cancer types. Because this analysis shows association rather than direction, both FKBP6-to-partner and partner-to-FKBP6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SULT6B1 grouped by FKBP6-low versus FKBP6-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FKBP6→partner) and Y-score (partner→FKBP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BREASTSULT6B1 →+0.012+5.169<.001.00531
BREASTOR5M3 →+0.030+5.781<.001.00131
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

SULT6B1 by FKBP6 expression — BREAST

Box plot of SULT6B1 in FKBP6-low vs FKBP6-high samples in BREAST.

Explore this box plot interactively →

Exploration