FKBP2

Across TCGA patient cohorts, FKBP2 mutation is significantly associated with the RNA expression of many other genes, with 31 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FKBP2-associated genes across cancer lineages are RNA5SP100, RNA5SP222, and RNU6-222P. Each is linked with FKBP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FKBP2-to-partner and partner-to-FKBP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP100 grouped by FKBP2-low versus FKBP2-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FKBP2→partner) and Y-score (partner→FKBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNA5SP100 →	+0.277	+8.055	<.001	.007	3	2
BRCA	RNA5SP222 →	+0.286	+7.731	<.001	.009	3	2
UCEC	RNU6-222P →	+1.009	+3.809	<.001	.007	3	2
BLCA	FTHL18 →	+0.065	+7.040	<.001	<.001	3	2
UCEC	SNORD11B →	+1.021	+4.061	<.001	.005	3	1
UCEC	RNA5SP414 →	+0.966	+3.840	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

RNA5SP100 by FKBP2 expression — BRCA

Explore this box plot interactively →