Q-omics provides the consensus-scored FTHL18 profile across patient tissues and cancer cell-line models. FTHL18 expression is associated with patient survival in 13 of 34 cancer types, with the highest sampling consensus in BRCA. Additionally, FTHL18 RNA expression shows 5,879 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight BRCA, and STAD as cancer lineages where FTHL18 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes FTHL18 survival associations across molecular data types. FTHL18 RNA expression shows survival associations in the most cancer types (13). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

FTHL18 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	13	BRCA (36)	view →

This table ranks reproducible FTHL18 RNA expression–survival associations across cancer types. High FTHL18 expression shows unfavorable associations in BRCA, UCS, SARC, LUSC and GBM, but favorable associations in PAAD. The BRCA Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .001). Together, the overview and detailed table identify BRCA as the clearest survival context for FTHL18 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	DFS	Tertile	All	0.140	1.000	.001	36	view →
UCS	DFS	Tertile	IV	0.132	0.718	.002	36	view →
PAAD	DFS	Tertile	All	0.840	0.258	.011	30	view →
SARC	OS	Tertile	All	0.309	0.776	<.001	27	view →
LUSC	OS	Tertile	All	0.425	0.663	.031	18	view →
GBM	OS	Tertile	All	0.020	0.416	<.001	18	view →

Pink = unfavorable, green = favorable. all 13 lineages →

FTHL18-BRCA (DFS)

Kaplan–Meier survival curve for FTHL18 RNA expression in BRCA: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with FTHL18 in patient tissues and cancer cell lines. In patient samples, FTHL18 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
Function (RNA)	5,879	STAD (5484)	view →
RNA	3,573	THCA (546)	view →