FKBP1B

Across TCGA cell cohorts, FKBP1B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,676 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible FKBP1B-associated GO terms across cancer lineages are Negative regulation of heart rate, Negative regulation of release of sequestered calcium ion into cytosol, and Ribonucleotide biosynthetic process. Each is linked with FKBP1B in more than 9 cancer types. Because this analysis shows association rather than direction, both FKBP1B-to-partner and partner-to-FKBP1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of heart rate grouped by FKBP1B-low versus FKBP1B-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FKBP1B→partner) and Y-score (partner→FKBP1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Negative regulation of heart rate →	-0.342	-1.884	<.001	<.001	3	10
LARGE_INTESTINE	Negative regulation of release of sequestered calcium ion into cytosol →	-0.132	-1.049	<.001	<.001	2	10
UPPER_AERODIGESTIVE_TRACT	Ribonucleotide biosynthetic process →	+0.055	+1.293	.007	.002	3	9
CNS	Ribose phosphate biosynthetic process →	+0.044	+0.876	.005	.008	3	8
OESOPHAGUS	NMDA glutamate receptor clustering →	+1.719	+1.658	<.001	.003	3	8
UPPER_AERODIGESTIVE_TRACT	Cytoplasmic translation →	+0.070	+1.278	.003	.002	2	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,676 associations by consensus.

Negative regulation of heart rate by FKBP1B expression — LARGE_INTESTINE

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