FJX1

Across TCGA patient cohorts, FJX1 mutation is significantly associated with the total protein of many other genes, with 11 significant associations in total. COAD shows the largest number of these associations.

The most reproducible FJX1-associated genes across cancer lineages are INPP4B, PREX1, and Rab25. Each is linked with FJX1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FJX1-to-partner and partner-to-FJX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, INPP4B grouped by FJX1-low versus FJX1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FJX1→partner) and Y-score (partner→FJX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	INPP4B →	-0.554	-3.161	.002	.019	3	1
COAD	PREX1 →	+0.208	+2.820	.042	.035	3	1
COAD	Rab25 →	-0.439	-3.161	<.001	.019	3	1
COAD	TSC1 →	-0.346	-3.161	.011	.019	3	1
COAD	c-Myc →	-0.242	-3.161	.037	.019	3	1
COAD	Cyclin-E1 →	+0.259	+2.820	.035	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

INPP4B by FJX1 expression — COAD

Explore this box plot interactively →