FJX1

Across TCGA pan-cancer cohorts, FJX1 RNA differs between tumor and matched normal tissue in 16 of 18 cancer types tested, making tumor–normal expression one of FJX1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where FJX1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types FJX1 is over-expressed in tumor, although a few such as KICH and UCEC show the opposite, repressed pattern.

COAD, KIRC, and HNSC are the cancer types where FJX1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FJX1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	II,III,IV	+2.290	<.001	12	view →
KIRC	Female	All	+1.678	<.001	12	view →
HNSC	Male	All	+1.604	<.001	12	view →
STAD	Male	II,III,IV	+1.567	<.001	9	view →
KIRP	Male	III,IV	+1.807	<.001	8	view →
THCA	Female	II,III,IV	+1.379	<.001	8	view →
READ	All	II,III,IV	+2.327	<.001	7	view →
LUSC	Male	II,III,IV	+1.934	<.001	7	view →
BLCA	Male	All	+1.334	.005	6	view →
KICH	All	All	−1.209	<.001	5	view →
LUAD	All	II,III,IV	+0.592	.009	5	view →
LIHC	All	All	+0.509	.001	5	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 16 lineages.

FJX1–COAD

Open the COAD breakdown →