FJX1

Across TCGA pan-cancer cohorts, FJX1 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated FJX1 data layer compared with 1 for mutation status.

The strongest signal is observed in uveal melanoma (UVM), where higher FJX1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated FJX1 expression acts as an unfavorable survival marker, although some lineages such as ESCA and THYM show a favorable association.

UVM, HNSC, and MESO are the cancer types where FJX1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Median	All	0.409	0.788	<.001	107	view →
HNSC	DFS	Quartile	All	0.608	0.788	<.001	90	view →
MESO	OS	Tertile	All	0.387	0.722	<.001	70	view →
KIRP	DFS	Median	All	0.836	0.979	<.001	59	view →
COAD	DFS	Tertile	All	0.630	0.777	.005	49	view →
ACC	OS	Tertile	II,III,IV	0.219	0.842	<.001	41	view →
LUAD	DFS	Quartile	All	0.207	0.475	<.001	31	view →
ESCA	DFS	Median	II,III,IV	1.000	0.399	.013	18	view →
TGCT	DFS	Quartile	All	0.671	0.947	.002	18	view →
SKCM	DFS	Median	III,IV	0.375	0.683	.001	17	view →
STAD	OS	Quartile	All	0.271	0.508	.007	17	view →
THCA	DFS	Tertile	IV	0.462	0.865	.012	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

FJX1–UVM (DFS)

Open the UVM breakdown →