FIGNL2

Across TCGA cell cohorts, FIGNL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,790 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FIGNL2-associated GO terms across cancer lineages are Heterochromatin formation, tRNA transcription, and Regulation of DNA repair. Each is linked with FIGNL2 in more than 9 cancer types. Because this analysis shows association rather than direction, both FIGNL2-to-partner and partner-to-FIGNL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Heterochromatin formation grouped by FIGNL2-low versus FIGNL2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FIGNL2→partner) and Y-score (partner→FIGNL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Heterochromatin formation →	+0.082	+0.220	<.001	<.001	3	10
OESOPHAGUS	tRNA transcription →	+0.084	+0.262	<.001	<.001	3	10
BONE	Regulation of DNA repair →	+0.084	+0.251	.001	.001	3	10
OESOPHAGUS	Spliceosomal complex assembly →	+0.085	+0.242	.001	.001	2	10
BONE	Epigenetic regulation of gene expression →	+0.060	+0.155	<.001	.001	3	9
STOMACH	Regulation of RNA splicing →	+0.095	+0.440	.001	.005	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,790 associations by consensus.

Heterochromatin formation by FIGNL2 expression — BONE

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