FIGNL2

Across TCGA pan-cancer cohorts, FIGNL2 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated FIGNL2 data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher FIGNL2 RNA is associated with better overall survival. In most high-consensus cancer types, elevated FIGNL2 expression acts as an unfavorable survival marker, although some lineages such as UCS and PAAD show a favorable association.

UCS, PAAD, and LUAD are the cancer types where FIGNL2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	OS	Quartile	II,III,IV	0.790	0.292	<.001	78	view →
PAAD	OS	Median	All	0.557	0.255	<.001	57	view →
LUAD	OS	Tertile	II,III,IV	0.690	0.479	.001	54	view →
UCEC	OS	Tertile	All	0.825	0.925	<.001	48	view →
THYM	OS	Median	II,III,IV	0.960	0.614	.002	40	view →
LGG	DFS	Median	All	0.670	0.802	<.001	40	view →
MESO	OS	Median	II,III,IV	0.308	0.493	.011	29	view →
LIHC	OS	Quartile	All	0.662	0.810	.011	21	view →
ACC	DFS	Tertile	All	0.390	0.748	.002	21	view →
LAML	DFS	Quartile	All	0.351	0.726	.004	18	view →
READ	OS	Quartile	All	0.804	0.315	.023	12	view →
KIRP	DFS	Median	III,IV	0.744	0.227	.028	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

FIGNL2–UCS (OS)

Open the UCS breakdown →