FIGNL2-DT

Across TCGA patient cohorts, FIGNL2-DT RNA expression is significantly associated with the go_rna of many other GO terms, with 7,162 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible FIGNL2-DT-associated GO terms across cancer lineages are Regulation of actin filament organization, Post-Golgi vesicle-mediated transport, and Regulation of protein polymerization. Each is linked with FIGNL2-DT in more than 27 cancer types. Because this analysis shows association rather than direction, both FIGNL2-DT-to-partner and partner-to-FIGNL2-DT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of actin filament organization grouped by FIGNL2-DT-low versus FIGNL2-DT-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FIGNL2-DT→partner) and Y-score (partner→FIGNL2-DT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of actin filament organization →	+0.062	+0.329	<.001	<.001	3	28
STAD	Post-Golgi vesicle-mediated transport →	+0.064	+0.329	<.001	<.001	3	28
STAD	Regulation of protein polymerization →	+0.057	+0.297	<.001	<.001	3	28
STAD	Regulation of small GTPase mediated signal transduction →	+0.054	+0.324	<.001	<.001	3	28
STAD	Cellular senescence →	+0.056	+0.358	<.001	<.001	3	27
UCS	Positive regulation of protein binding →	+0.061	+1.322	<.001	.001	3	27

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,162 associations by consensus.

Regulation of actin filament organization by FIGNL2-DT expression — STAD

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