FGF8

Across TCGA patient cohorts, FGF8 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,002 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FGF8-associated proteins across cancer lineages are TBC1D9B, TICRR_S923, and TPX2. Each is linked with FGF8 in more than 2 cancer types. Because this analysis shows association rather than direction, both FGF8-to-partner and partner-to-FGF8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FGF8 versus TBC1D9B in LSCC, with a Pearson correlation of -0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FGF8→partner) and Y-score (partner→FGF8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TBC1D9B →	-0.203	-0.341	<.001	.001	3	3
BRCA	TICRR_S923 →	+0.856	+0.213	.001	.002	3	3
LSCC	TPX2 →	+0.680	+0.347	<.001	.003	3	3
LSCC	WDR12 →	+0.481	+0.348	<.001	.008	3	3
BRCA	SSH3 →	-0.462	-0.166	<.001	.002	3	3
UCEC	NIPBL_T592 →	+0.479	+0.967	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,002 associations by consensus.

FGF8 vs TBC1D9B — LSCC

Explore this scatter interactively →