FGF6

Across TCGA patient cohorts, FGF6 protein abundance is significantly associated with the RNA expression of many other genes, with 1,427 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible FGF6-associated genes across cancer lineages are RIPOR2, GDF15, and COL4A3. Each is linked with FGF6 in more than 1 cancer types. Because this analysis shows association rather than direction, both FGF6-to-partner and partner-to-FGF6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FGF6 versus RIPOR2 in BRCA, with a Pearson correlation of -0.55.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FGF6→partner) and Y-score (partner→FGF6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RIPOR2 →	-1.535	-1.776	.001	.003	3	2
BRCA	GDF15 →	+2.217	+1.270	<.001	.001	3	2
BRCA	COL4A3 →	-1.452	-1.170	.001	.003	3	2
BRCA	SERPINA4 →	+0.738	+1.609	.002	<.001	3	1
BRCA	RIMS4 →	+4.218	+1.278	<.001	.005	3	1
BRCA	RASSF2 →	-1.621	-1.589	.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,427 associations by consensus.

FGF6 vs RIPOR2 — BRCA

Explore this scatter interactively →