FGF13

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FGF13 mutation is significantly associated with the RNA expression of many other genes, with 3,723 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FGF13-associated genes across cancer lineages are RPL23AP94, MIR548S, and MIR6779. Each is linked with FGF13 in more than 2 cancer types. Because this analysis shows association rather than direction, both FGF13-to-partner and partner-to-FGF13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPL23AP94 grouped by FGF13-low versus FGF13-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FGF13→partner) and Y-score (partner→FGF13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCARPL23AP94 →+0.080+4.147<.001.00933
CESCMIR548S →+0.656+6.003<.001<.00133
READMIR6779 →+1.279+4.827<.001.00233
UCECHSPA6 →+0.779+1.536.001.00233
UCECCENPA →+0.470+1.736.009<.00133
UCECSMU1 →+0.290+1.347.002.00733
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,723 associations by consensus.

RPL23AP94 by FGF13 expression — BLCA

Box plot of RPL23AP94 in FGF13-low vs FGF13-high samples in BLCA.

Explore this box plot interactively →

Exploration