FGF13

Across TCGA pan-cancer cohorts, FGF13 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated FGF13 data layer compared with 2 for mutation status and 1 for mass-spec protein.

The strongest signal is observed in brain lower grade glioma (LGG), where higher FGF13 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated FGF13 expression acts as an unfavorable survival marker, although some lineages such as LGG and LAML show a favorable association.

LGG, LAML, and LIHC are the cancer types where FGF13 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LGG	DFS	Tertile	All	0.799	0.598	<.001	43	view →
LAML	DFS	Median	All	0.475	0.275	.006	36	view →
LIHC	OS	Quartile	All	0.539	0.790	.001	26	view →
UCS	DFS	Quartile	II,III,IV	0.594	0.122	.011	24	view →
UVM	OS	Median	All	0.397	0.845	.003	21	view →
SCLC	DFS	Tertile	III,IV	0.233	0.863	.017	18	view →
KIRP	DFS	Median	III,IV	0.431	0.900	.016	18	view →
KIRC	OS	Quartile	All	0.758	0.561	.002	17	view →
PAAD	OS	Tertile	All	0.723	0.480	.006	17	view →
LUSC	OS	Quartile	All	0.823	0.699	.015	15	view →
COAD	DFS	Median	III,IV	0.547	0.733	.015	13	view →
ACC	OS	Median	III,IV	0.321	0.789	.011	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

FGF13–LGG (DFS)

Open the LGG breakdown →