FGF13

Across TCGA patient cohorts, FGF13 mutation is significantly associated with the total protein of many other genes, with 37 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FGF13-associated genes across cancer lineages are eEF2, S6_pS240_S244, and eIF4E. Each is linked with FGF13 in more than 2 cancer types. Because this analysis shows association rather than direction, both FGF13-to-partner and partner-to-FGF13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eEF2 grouped by FGF13-low versus FGF13-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FGF13→partner) and Y-score (partner→FGF13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.326	+2.906	.004	.001	3	3
UCEC	S6_pS240_S244 →	+0.306	+2.415	.018	.003	3	3
UCEC	eIF4E →	+0.215	+2.920	.001	<.001	3	2
UCEC	ERK2 →	+0.189	+1.662	.002	.010	3	2
UCEC	MEK1 →	+0.371	+2.247	.001	.001	3	2
UCEC	Rictor_pT1135 →	-0.073	-2.115	.025	.017	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 37 associations by consensus.

eEF2 by FGF13 expression — UCEC

Explore this box plot interactively →