FGF13

Across TCGA cell cohorts, FGF13 mutation is significantly associated with the RNA expression of many other genes, with 256 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FGF13-associated genes across cancer lineages are TCP11X1, IFNA8, and SCGB1C1. Each is linked with FGF13 in more than 1 cancer types. Because this analysis shows association rather than direction, both FGF13-to-partner and partner-to-FGF13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TCP11X1 grouped by FGF13-low versus FGF13-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FGF13→partner) and Y-score (partner→FGF13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	TCP11X1 →	+0.006	+5.415	.007	.004	3	2
SOFT_TISSUE	IFNA8 →	+0.034	+4.930	<.001	.008	3	1
SOFT_TISSUE	SCGB1C1 →	+0.073	+5.977	<.001	.001	3	1
SOFT_TISSUE	MROH5 →	+0.021	+4.930	<.001	.008	3	1
SKIN	TMEM95 →	+0.034	+4.977	<.001	.007	3	1
LARGE_INTESTINE	CBY1 →	+0.658	+3.451	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 256 associations by consensus.

TCP11X1 by FGF13 expression — SKIN

Explore this box plot interactively →