FGF1

Across TCGA patient cohorts, FGF1 protein abundance is significantly associated with the RNA expression of many other genes, with 13,945 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible FGF1-associated genes across cancer lineages are MEIS3, RASGRF2, and PDGFRB. Each is linked with FGF1 in more than 5 cancer types. Because this analysis shows association rather than direction, both FGF1-to-partner and partner-to-FGF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FGF1 versus MEIS3 in OV, with a Pearson correlation of 0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FGF1→partner) and Y-score (partner→FGF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MEIS3 →	+1.152	+0.742	<.001	<.001	3	6
OV	RASGRF2 →	+0.948	+0.725	.001	<.001	3	6
OV	PDGFRB →	+1.239	+0.634	.001	<.001	3	6
OV	OLFML3 →	+1.510	+0.793	.002	<.001	3	6
BRCA	CNRIP1 →	+0.880	+0.699	<.001	<.001	3	6
CCRCC	ISLR →	+1.190	+0.450	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,945 associations by consensus.

FGF1 vs MEIS3 — OV

Explore this scatter interactively →