FES

Across TCGA patient cohorts, FES protein abundance is significantly associated with the RNA expression of many other genes, with 20,196 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FES-associated genes across cancer lineages are SAMSN1, SELL, and CSF2RB. Each is linked with FES in more than 9 cancer types. Because this analysis shows association rather than direction, both FES-to-partner and partner-to-FES results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FES versus SAMSN1 in GBM, with a Pearson correlation of 0.61.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FES→partner) and Y-score (partner→FES) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SAMSN1 →	+0.982	+0.534	<.001	<.001	3	10
GBM	SELL →	+1.399	+0.528	<.001	<.001	3	10
GBM	CSF2RB →	+1.105	+0.641	<.001	<.001	3	9
GBM	BTK →	+0.790	+0.465	<.001	<.001	3	9
GBM	IL10RA →	+1.190	+0.546	<.001	<.001	3	9
GBM	PLEK →	+1.264	+0.633	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,196 associations by consensus.

FES vs SAMSN1 — GBM

Explore this scatter interactively →