FES

Across TCGA cell cohorts, FES RNA expression is significantly associated with the go_rna of many other GO terms, with 3,444 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FES-associated GO terms across cancer lineages are Viral gene expression, Positive regulation of triglyceride metabolic process, and Positive regulation of ubiquitin-dependent protein catabolic process. Each is linked with FES in more than 5 cancer types. Because this analysis shows association rather than direction, both FES-to-partner and partner-to-FES results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Viral gene expression grouped by FES-low versus FES-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FES→partner) and Y-score (partner→FES) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Viral gene expression →	+0.095	+1.221	.001	.001	3	6
BONE	Positive regulation of triglyceride metabolic process →	+0.088	+1.213	.001	.001	3	6
LARGE_INTESTINE	Positive regulation of ubiquitin-dependent protein catabolic process →	+0.064	+1.147	<.001	<.001	3	6
LARGE_INTESTINE	Viral life cycle →	+0.069	+1.032	<.001	<.001	3	6
BLOOD_Lymphoma	Negative regulation of syncytium formation by plasma membrane fusion →	+0.093	+1.748	<.001	<.001	3	6
LARGE_INTESTINE	Protein stabilization →	+0.049	+0.636	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,444 associations by consensus.

Viral gene expression by FES expression — BONE

Explore this box plot interactively →