FERD3L

Across TCGA cell cohorts, FERD3L mutation is significantly associated with the RNA expression of many other genes, with 24 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible FERD3L-associated genes across cancer lineages are OR1E2, APOL5, and TMEM95. Each is linked with FERD3L in more than 1 cancer types. Because this analysis shows association rather than direction, both FERD3L-to-partner and partner-to-FERD3L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR1E2 grouped by FERD3L-low versus FERD3L-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FERD3L→partner) and Y-score (partner→FERD3L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OR1E2 →	+0.013	+4.078	<.001	.009	3	1
LUNG_NSCLC_LUAD	APOL5 →	+0.040	+4.093	<.001	.004	3	1
LUNG_NSCLC_LUAD	TMEM95 →	+0.015	+3.544	.004	.009	3	1
LUNG_NSCLC_LUAD	OPALIN →	+0.006	+3.977	.008	.005	3	1
LUNG_NSCLC_LUAD	OR51G1 →	+0.015	+4.078	<.001	.009	3	1
LARGE_INTESTINE	C14orf180 →	+0.126	+4.155	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

OR1E2 by FERD3L expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →