FERD3L

Across TCGA pan-cancer cohorts, FERD3L RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated FERD3L data layer compared with 7 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher FERD3L RNA is associated with worse overall survival. In most high-consensus cancer types, elevated FERD3L expression acts as an unfavorable survival marker, although some lineages such as SARC and STAD show a favorable association.

UCEC, KIRC, and THCA are the cancer types where FERD3L RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Tertile	All	0.123	0.927	<.001	108	view →
KIRC	OS	Tertile	II,III,IV	0.546	0.792	.007	84	view →
THCA	DFS	Tertile	III,IV	0.172	0.829	<.001	84	view →
LUSC	OS	Tertile	III,IV	0.203	0.679	<.001	81	view →
READ	DFS	Tertile	All	0.194	0.852	<.001	72	view →
KIRP	DFS	Tertile	All	0.519	0.912	<.001	60	view →
LIHC	OS	Tertile	II,III,IV	0.179	0.719	<.001	51	view →
MESO	OS	Tertile	All	0.219	0.557	.003	36	view →
COAD	OS	Tertile	IV	0.039	0.660	<.001	36	view →
LGG	DFS	Quartile	All	0.286	0.459	<.001	33	view →
UVM	OS	Tertile	III,IV	0.104	0.813	.001	27	view →
SARC	DFS	Tertile	All	0.728	0.486	.010	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

FERD3L–UCEC (OS)

Open the UCEC breakdown →