FER1L5

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FER1L5 mutation is significantly associated with the RNA expression of many other genes, with 5,634 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FER1L5-associated genes across cancer lineages are RN7SKP50, OR51H1, and MIR6771. Each is linked with FER1L5 in more than 2 cancer types. Because this analysis shows association rather than direction, both FER1L5-to-partner and partner-to-FER1L5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP50 grouped by FER1L5-low versus FER1L5-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FER1L5→partner) and Y-score (partner→FER1L5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCARN7SKP50 →+0.412+2.693<.001.00733
CESCOR51H1 →+0.016+4.164<.001.00633
LUADMIR6771 →+0.569+5.712<.001.00333
UCECMED31 →+0.506+2.458<.001<.00133
COADYWHAE →+0.470+2.598<.001<.00133
UCECKISS1R →+0.792+1.412<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,634 associations by consensus.

RN7SKP50 by FER1L5 expression — BRCA

Box plot of RN7SKP50 in FER1L5-low vs FER1L5-high samples in BRCA.

Explore this box plot interactively →

Exploration