FER1L4

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FER1L4 mutation is significantly associated with the RNA expression of many other genes, with 2,065 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FER1L4-associated genes across cancer lineages are FBXL12P1, CNOT4P1, and PIEZO1P2. Each is linked with FER1L4 in more than 1 cancer types. Because this analysis shows association rather than direction, both FER1L4-to-partner and partner-to-FER1L4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FBXL12P1 grouped by FER1L4-low versus FER1L4-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FER1L4→partner) and Y-score (partner→FER1L4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCFBXL12P1 →+0.053+4.757<.001.00431
CESCCNOT4P1 →+0.032+4.507<.001.00131
CESCPIEZO1P2 →+0.018+3.816.004.00731
CESCOR2A15P →+0.045+3.760.001.00731
CESCRNU6-948P →+0.516+4.133<.001.00431
CESCRN7SL25P →+0.264+4.567<.001.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,065 associations by consensus.

FBXL12P1 by FER1L4 expression — CESC

Box plot of FBXL12P1 in FER1L4-low vs FER1L4-high samples in CESC.

Explore this box plot interactively →

Exploration