FER1L4

Across TCGA pan-cancer cohorts, FER1L4 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated FER1L4 data layer compared with 3 for mass-spec protein.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher FER1L4 RNA is associated with better overall survival. In most high-consensus cancer types, elevated FER1L4 expression acts as an unfavorable survival marker, although some lineages such as BLCA and SKCM show a favorable association.

BLCA, MESO, and KIRP are the cancer types where FER1L4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Median	All	0.699	0.524	<.001	111	view →
MESO	OS	Tertile	All	0.271	0.580	<.001	109	view →
KIRP	DFS	Tertile	III,IV	0.103	0.582	.001	90	view →
KIRC	DFS	Median	All	0.522	0.705	<.001	85	view →
SKCM	DFS	Median	All	0.266	0.150	<.001	77	view →
ACC	DFS	Median	All	0.417	0.742	<.001	69	view →
UCS	DFS	Median	IV	0.440	0.885	.015	48	view →
LGG	DFS	Median	All	0.263	0.483	<.001	40	view →
UVM	DFS	Median	III,IV	0.208	0.740	.006	30	view →
PRAD	DFS	Median	All	0.838	0.926	<.001	24	view →
GBM	OS	Tertile	All	0.197	0.322	.004	21	view →
LIHC	DFS	Tertile	All	0.453	0.592	.004	21	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

FER1L4–BLCA (OS)

Open the BLCA breakdown →