FEM1C

Across TCGA patient cohorts, FEM1C mutation is significantly associated with the RNA expression of many other genes, with 3,133 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FEM1C-associated genes across cancer lineages are MIR3927, DEFB106A, and LINC01097. Each is linked with FEM1C in more than 1 cancer types. Because this analysis shows association rather than direction, both FEM1C-to-partner and partner-to-FEM1C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR3927 grouped by FEM1C-low versus FEM1C-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FEM1C→partner) and Y-score (partner→FEM1C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	MIR3927 →	+0.311	+4.433	<.001	.007	3	2
LGG	DEFB106A →	+0.129	+7.977	<.001	.007	3	2
KIRP	LINC01097 →	+0.040	+5.060	<.001	.008	3	2
COAD	H3P9 →	+0.429	+5.602	<.001	.004	3	2
CESC	MIR450A1 →	+0.460	+4.812	<.001	.006	3	2
LUAD	RNU6-1213P →	+0.508	+7.930	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,133 associations by consensus.

MIR3927 by FEM1C expression — BLCA

Explore this box plot interactively →