Q-omics provides the consensus-scored DEFB106A profile across patient tissues and cancer cell-line models. DEFB106A expression is associated with patient survival in 3 of 34 cancer types, with the highest sampling consensus in LUSC. Additionally, DEFB106A RNA expression shows 5,874 significant gene co-expression associations, with the highest sampling consensus in LUSC. Together, these results highlight LUSC as cancer lineages where DEFB106A shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes DEFB106A survival associations across molecular data types. DEFB106A RNA expression shows survival associations in the most cancer types (3). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

DEFB106A data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	3	LUSC (63)	view →

This table ranks reproducible DEFB106A RNA expression–survival associations across cancer types. High DEFB106A expression shows unfavorable associations in LUSC, HNSC and KIRC. The LUSC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify LUSC as the clearest survival context for DEFB106A RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	OS	Tertile	All	0.133	0.762	<.001	63	view →
HNSC	OS	Tertile	III,IV	0.272	0.660	.030	18	view →
KIRC	DFS	Tertile	All	0.266	0.796	.020	18	view →

Pink = unfavorable, green = favorable. all 3 lineages →

DEFB106A-LUSC (OS)

Kaplan–Meier survival curve for DEFB106A RNA expression in LUSC: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with DEFB106A in patient tissues and cancer cell lines. In patient samples, DEFB106A shows the broadest associations at the RNA and protein expression levels, with LUSC recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
RNA	5,874	LUSC (4667)	view →
Function (RNA)	5,195	STAD (5186)	view →