Q-omics provides the consensus-scored FDPSP3 profile across patient tissues and cancer cell-line models. FDPSP3 expression is associated with patient survival in 18 of 34 cancer types, with the highest sampling consensus in ACC. Among the 18 cancer types available for tumor–normal comparison, FDPSP3 is differentially expressed in 5, with the highest sampling consensus in LUSC. Additionally, FDPSP3 RNA expression shows 9,606 significant protein co-abundance associations, with the highest sampling consensus in GBM. Together, these results highlight ACC, LUSC, and GBM as cancer lineages where FDPSP3 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for FDPSP3 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes FDPSP3 survival associations across molecular data types. FDPSP3 RNA expression shows survival associations in the most cancer types (18). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible FDPSP3 RNA expression–survival associations across cancer types. High FDPSP3 expression shows unfavorable associations in ACC, KIRC, KICH and TGCT, but favorable associations in HNSC and PAAD. The ACC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify ACC as the clearest survival context for FDPSP3 RNA expression.
This table summarizes FDPSP3 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 5. The strongest signals are observed in LUSC for RNA.
This table ranks reproducible tumor–normal expression differences for FDPSP3. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. FDPSP3 shows higher tumor expression in LUSC, KIRC, COAD, STAD and LIHC. The LUSC box plot shows higher FDPSP3 RNA expression in tumor versus normal tissue (log2 FC = +0.091, t-test p = .009).
This table shows molecular features associated with FDPSP3 in patient tissues and cancer cell lines. In patient samples, FDPSP3 shows the broadest associations at the RNA and protein expression levels, with GBM recurring as the lineage with the largest associated feature set.
