FCGR2A

Across TCGA patient cohorts, FCGR2A protein abundance is significantly associated with the RNA expression of many other genes, with 11,752 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FCGR2A-associated genes across cancer lineages are CD33, HRH2, and SIGLEC9. Each is linked with FCGR2A in more than 4 cancer types. Because this analysis shows association rather than direction, both FCGR2A-to-partner and partner-to-FCGR2A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FCGR2A versus CD33 in OV, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FCGR2A→partner) and Y-score (partner→FCGR2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CD33 →	+0.670	+0.457	.002	<.001	3	5
LSCC	HRH2 →	+0.632	+0.327	<.001	<.001	3	5
GBM	SIGLEC9 →	+0.921	+0.669	<.001	<.001	3	5
CCRCC	ITGAX →	+0.958	+0.705	<.001	.001	3	5
GBM	LAIR1 →	+1.070	+0.726	<.001	<.001	3	5
OV	ADAP2 →	+0.874	+0.362	.001	.007	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,752 associations by consensus.

FCGR2A vs CD33 — OV

Explore this scatter interactively →