FCGR2A

Across TCGA cell cohorts, FCGR2A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,963 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FCGR2A-associated GO terms across cancer lineages are Antibody-dependent cellular cytotoxicity, Type IIa hypersensitivity, and Type II hypersensitivity. Each is linked with FCGR2A in more than 17 cancer types. Because this analysis shows association rather than direction, both FCGR2A-to-partner and partner-to-FCGR2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Antibody-dependent cellular cytotoxicity grouped by FCGR2A-low versus FCGR2A-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FCGR2A→partner) and Y-score (partner→FCGR2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Antibody-dependent cellular cytotoxicity →	+1.465	+3.228	<.001	<.001	3	18
BLOOD_Leukemia	Type IIa hypersensitivity →	+1.465	+3.228	<.001	<.001	3	18
BLOOD_Leukemia	Type II hypersensitivity →	+1.465	+3.228	<.001	<.001	3	18
LIVER	Viral process →	+0.083	+1.412	.006	.004	2	10
LUNG_NSCLC_LUAD	Neural crest cell migration involved in autonomic nervous system development →	+0.547	+1.476	<.001	<.001	3	6
UPPER_AERODIGESTIVE_TRACT	Defense response to virus →	+0.055	+0.452	.006	.007	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,963 associations by consensus.

Antibody-dependent cellular cytotoxicity by FCGR2A expression — BLOOD_Leukemia

Explore this box plot interactively →