FBXW11

Across TCGA patient cohorts, FBXW11 protein abundance is significantly associated with the RNA expression of many other genes, with 10,364 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible FBXW11-associated genes across cancer lineages are DHX37, MCEMP1, and ARL13B. Each is linked with FBXW11 in more than 2 cancer types. Because this analysis shows association rather than direction, both FBXW11-to-partner and partner-to-FBXW11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FBXW11 versus DHX37 in LSCC, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXW11→partner) and Y-score (partner→FBXW11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DHX37 →	-0.430	-0.213	<.001	<.001	3	3
PDAC	MCEMP1 →	+0.949	+0.365	.002	.002	3	3
OV	ARL13B →	-0.612	-0.891	.008	.002	3	2
UCEC	FRMPD2B →	-0.887	-0.137	.001	.002	3	2
UCEC	DHRS4-AS1 →	-0.451	-0.200	.006	.002	3	2
UCEC	RPL39P16 →	-0.629	-0.199	.004	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,364 associations by consensus.

FBXW11 vs DHX37 — LSCC

Explore this scatter interactively →