FBXO5

Across TCGA patient cohorts, FBXO5 RNA expression is significantly associated with the protein abundance of many other proteins, with 22,810 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FBXO5-associated proteins across cancer lineages are RPL12_S38, RRM2, and SMC2. Each is linked with FBXO5 in more than 9 cancer types. Because this analysis shows association rather than direction, both FBXO5-to-partner and partner-to-FBXO5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FBXO5 versus RPL12_S38 in LUAD, with a Pearson correlation of 0.68.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO5→partner) and Y-score (partner→FBXO5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RPL12_S38 →	+1.267	+0.805	<.001	<.001	3	10
LUAD	RRM2 →	+0.978	+0.854	<.001	<.001	3	10
UCEC	SMC2 →	+0.836	+0.976	<.001	<.001	3	10
UCEC	SMC4 →	+0.798	+0.973	<.001	<.001	3	10
UCEC	TK1 →	+0.808	+0.962	<.001	<.001	3	10
LUAD	TOP2A_S1106 →	+1.301	+0.817	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,810 associations by consensus.

FBXO5 vs RPL12_S38 — LUAD

Explore this scatter interactively →