FBXO32

Across TCGA cell cohorts, FBXO32 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FBXO32-associated genes across cancer lineages are CCDC54, MDGA2, and OR2C1. Each is linked with FBXO32 in more than 1 cancer types. Because this analysis shows association rather than direction, both FBXO32-to-partner and partner-to-FBXO32 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCDC54 grouped by FBXO32-low versus FBXO32-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO32→partner) and Y-score (partner→FBXO32) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CCDC54 →	+0.164	+3.736	<.001	.004	3	1
LARGE_INTESTINE	MDGA2 →	+0.182	+3.854	<.001	.006	3	1
LARGE_INTESTINE	OR2C1 →	+0.151	+3.725	<.001	.008	3	1
LARGE_INTESTINE	INSL5 →	+0.368	+3.626	<.001	.006	3	1
LARGE_INTESTINE	IQCF6 →	+0.228	+3.882	<.001	.001	3	1
LARGE_INTESTINE	ARMH2 →	+0.184	+3.345	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

CCDC54 by FBXO32 expression — LARGE_INTESTINE

Explore this box plot interactively →