FBXO32

Across TCGA pan-cancer cohorts, FBXO32 RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of FBXO32’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where FBXO32 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types FBXO32 is over-expressed in tumor, although a few such as COAD and READ show the opposite, repressed pattern.

LUAD, COAD, and LIHC are the cancer types where FBXO32 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FBXO32 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Male	III,IV	+2.783	<.001	11	view →
COAD	Female	All	−1.676	<.001	8	view →
LIHC	Male	II,III,IV	+1.650	<.001	8	view →
READ	All	All	−2.353	<.001	7	view →
LUSC	Female	All	+2.092	<.001	7	view →
BLCA	All	III,IV	−1.467	.014	7	view →
UCEC	All	All	−4.044	<.001	6	view →
BRCA	Female	All	−0.910	<.001	6	view →
KIRC	All	All	+0.363	<.001	6	view →
CHOL	Male	All	+2.216	<.001	5	view →
KICH	All	II,III,IV	+0.864	.016	4	view →
STAD	Female	All	−2.451	.001	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 15 lineages.

FBXO32–LUAD

Open the LUAD breakdown →