FBXO3-DT

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FBXO3-DT RNA expression is significantly associated with the go_rna of many other GO terms, with 6,646 significant associations in total. STAD shows the largest number of these associations.

The most reproducible FBXO3-DT-associated GO terms across cancer lineages are ATP biosynthetic process, Cellular respiration, and Proton motive force-driven ATP synthesis. Each is linked with FBXO3-DT in more than 9 cancer types. Because this analysis shows association rather than direction, both FBXO3-DT-to-partner and partner-to-FBXO3-DT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATP biosynthetic process grouped by FBXO3-DT-low versus FBXO3-DT-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO3-DT→partner) and Y-score (partner→FBXO3-DT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STADATP biosynthetic process →+0.101+0.150<.001<.001310
STADCellular respiration →+0.097+0.157<.001<.001310
STADProton motive force-driven ATP synthesis →+0.106+0.138<.001<.00139
STADRegulation of protein folding →+0.081+0.132<.001<.00139
STADElectron transport chain →+0.091+0.159<.001<.00139
STADSCF-dependent proteasomal ubiquitin-dependent protein catabolic process →+0.070+0.147<.001<.00138
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,646 associations by consensus.

ATP biosynthetic process by FBXO3-DT expression — STAD

Box plot of ATP biosynthetic process in FBXO3-DT-low vs FBXO3-DT-high samples in STAD.

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Exploration