FBXO25

Across TCGA patient cohorts, FBXO25 mutation is significantly associated with the RNA expression of many other genes, with 513 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FBXO25-associated genes across cancer lineages are NF1P10, RNU4-58P, and RN7SL134P. Each is linked with FBXO25 in more than 1 cancer types. Because this analysis shows association rather than direction, both FBXO25-to-partner and partner-to-FBXO25 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NF1P10 grouped by FBXO25-low versus FBXO25-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO25→partner) and Y-score (partner→FBXO25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	NF1P10 →	+0.235	+6.569	<.001	.001	3	2
UCEC	RNU4-58P →	+0.213	+2.674	.002	.006	3	2
UCEC	RN7SL134P →	+0.144	+2.599	<.001	.003	3	2
CESC	LINC02559 →	+1.780	+6.342	<.001	.001	3	1
CESC	NPAP1P6 →	+0.015	+5.010	<.001	.009	3	1
CESC	PEX5L-AS2 →	+0.650	+5.306	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 513 associations by consensus.

NF1P10 by FBXO25 expression — CESC

Explore this box plot interactively →