FAT3

Across TCGA patient cohorts, FAT3 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,860 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible FAT3-associated proteins across cancer lineages are FERMT2, LRP1, and TLN2. Each is linked with FAT3 in more than 8 cancer types. Because this analysis shows association rather than direction, both FAT3-to-partner and partner-to-FAT3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAT3 versus FERMT2 in BRCA, with a Pearson correlation of 0.49.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FAT3→partner) and Y-score (partner→FAT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	FERMT2 →	+0.723	+0.347	<.001	<.001	3	9
BRCA	LRP1 →	+0.725	+0.327	<.001	<.001	3	8
BRCA	TLN2 →	+0.761	+0.357	<.001	<.001	3	8
BRCA	SGCD →	+0.816	+0.302	<.001	<.001	3	8
CCRCC	THBS3 →	+0.698	+0.750	<.001	<.001	3	8
BRCA	TIMP2 →	+0.793	+0.250	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,860 associations by consensus.

FAT3 vs FERMT2 — BRCA

Explore this scatter interactively →