FASLG

Across TCGA cell cohorts, FASLG RNA expression is significantly associated with the go_rna of many other GO terms, with 1,039 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible FASLG-associated GO terms across cancer lineages are Regulation of metanephric nephron tubule epithelial cell differentiation, Positive regulation of fibroblast proliferation, and Epithelial cell proliferation. Each is linked with FASLG in more than 4 cancer types. Because this analysis shows association rather than direction, both FASLG-to-partner and partner-to-FASLG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of metanephric nephron tubule epithelial cell differentiation grouped by FASLG-low versus FASLG-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FASLG→partner) and Y-score (partner→FASLG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Regulation of metanephric nephron tubule epithelial cell differentiation →	+0.181	+0.029	<.001	.002	3	5
LARGE_INTESTINE	Positive regulation of fibroblast proliferation →	+0.065	+0.801	.002	.006	3	4
PANCREAS	Epithelial cell proliferation →	+0.087	+0.022	<.001	.003	3	4
LIVER	Positive regulation of macrophage differentiation →	+0.247	+0.045	.001	.004	3	4
LARGE_INTESTINE	L-alanine transmembrane transport →	+0.138	+0.736	.001	.007	3	4
LARGE_INTESTINE	Regulation of CD8-positive, alpha-beta T cell differentiation →	+0.094	+0.780	.006	.009	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,039 associations by consensus.

Regulation of metanephric nephron tubule epithelial cell differentiation by FASLG expression — PANCREAS

Explore this box plot interactively →