Across TCGA patient cohorts, FANK1 mutation is significantly associated with the RNA expression of many other genes, with 1,702 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FANK1-associated genes across cancer lineages are SERPINE4P, C7orf66, and MIR190B. Each is linked with FANK1 in more than 2 cancer types. Because this analysis shows association rather than direction, both FANK1-to-partner and partner-to-FANK1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FANK1→partner) and Y-score (partner→FANK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	SERPINE4P →	+0.122	+5.444	<.001	.002	3	3
UCEC	C7orf66 →	+0.235	+2.019	<.001	.005	3	2
LUAD	MIR190B →	+0.376	+5.087	<.001	.004	3	2
LIHC	HAUS1P2 →	+0.070	+4.206	.001	.004	3	2
LIHC	RPS2P39 →	+0.041	+4.293	<.001	.009	3	2
LIHC	RN7SL18P →	+0.125	+3.964	.004	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,702 associations by consensus.

Exploration

FANK1 survival (RNA) · tumor vs normal (RNA) · all FANK1 data types