FANCG

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FANCG RNA expression is significantly associated with the protein abundance of many other proteins, with 19,040 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FANCG-associated proteins across cancer lineages are SMC2, SMU1, and TOP2A. Each is linked with FANCG in more than 8 cancer types. Because this analysis shows association rather than direction, both FANCG-to-partner and partner-to-FANCG results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FANCG→partner) and Y-score (partner→FANCG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADSMC2 →+0.601+0.366<.001<.00139
GBMSMU1 →+0.210+0.454<.001<.00139
LUADTOP2A →+0.932+0.261<.001<.00139
GBMRFC3 →+0.302+0.447<.001<.00138
UCECATAD2_S342 →+1.347+0.520<.001<.00138
LUADSMC4 →+0.607+0.355<.001<.00138
Each partner links to its Q-omics profile. Showing the 6 strongest of 19,040 associations by consensus.

Exploration